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Polymer Chemistry

We develop strategies for directly synthesising functional polymers in living system. This offers a platform to manipulate, track and control cellular behaviour by the in cellulo generation of macromolecules that have the ability to alter cellular motility, label cells by the generation of fluorescent polymers for long-term tracking studies, as well as the generation within cells of a variety of novel nanostructures.

Recent Publications

J. Geng, W. Li, Y. Zhang, N. Thottappillil, J. Clavadetscher, M. Bradley. Radical Polymerisation inside Living Cells. Nature Chemistry. 2019. 11, 578 - 586.

Y Zhang, M Üçüncü, A Gambardella, A Baibek, J Geng, S Zhang, J Clavadetscher, I Litzen, M Bradley* and A Lilienkampf. Bioorthogonal Swarming: in situ Generation of Dendrimers. J. Am. Chem. Soc., 2020, 142, 52, 21615–21621.

Yichuan Zhang, M.Bradley, J. Geng*, Photo-controlled one-pot strategy for the synthesis of asymmetric three-arm star polymers. Polymer Chemistry, 2019, 10, 4769-4773.